SCHEMBL29899643

SCHEMBL29899643

Oc1ccc2c(ccc3c2ccc2c4ccc(O)cc4ccc23)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.55
ESR1 P03372 7/20 0.50
ESR2 Q92731 7/20 0.50
ALOX15 P16050 2/20 0.50
HSD17B10 Q99714 2/20 0.50
CYP3A4 P08684 2/20 0.50
TSHR P16473 1/20 0.50
HIF1A Q16665 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LMNA P02545 2/20 0.48
MEN1 O00255 1/20 0.48
POLB P06746 1/20 0.48
KMT2A Q03164 1/20 0.48
HNF4A P41235 1/20 0.47
ABL1 P00519 1/20 0.46
ABCB1 P08183 1/20 0.46
BCR P11274 1/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1692369 1.00 CYP1A2 (0.55) CYP1A2ESR1ESR2ALOX15HSD17B10
SCHEMBL1533447 0.97 CYP1A2 (0.57) CYP1A2ESR1ESR2ALOX15HSD17B10
SCHEMBL6369167 0.89 CYP1A2 (0.50) CYP1A2ESR1ESR2ALOX15HSD17B10
SCHEMBL12473664 0.88 HPRT1 (0.64) CYP1A2HSD17B10TSHRHIF1ATDP1
SCHEMBL27289927 0.88 HPRT1 (0.64) CYP1A2HSD17B10TSHRHIF1ATDP1
SCHEMBL31503137 0.86 PTPN22 (0.45) CYP1A2ESR1ESR2
SCHEMBL1170838 0.85 CYP1A2 (0.65) CYP1A2ESR1ESR2HSD17B10TSHR
SCHEMBL9353832 0.84 TRPM4 (0.54) CYP1A2ESR1ESR2CYP3A4CYP2D6
SCHEMBL15869807 0.83 CYP1A2 (0.52) CYP1A2ESR1ESR2ALOX15HSD17B10
SCHEMBL1461934 0.83 ERN1 (0.52) CYP1A2ESR1ESR2ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2022122514-A 3,10-DIHYDROXYPICENE, METHOD FOR PRODUCING 3,10-DIHYDROXYPICENE, REFRACTIVE INDEX INCREASING AGENT, AND POLYESTER RESIN 国立大学法人 岡山大学 2022-08-23 JP disclosed
JP-2022122514-A 3,10-DIHYDROXYPICENE, METHOD FOR PRODUCING 3,10-DIHYDROXYPICENE, REFRACTIVE INDEX INCREASING AGENT, AND POLYESTER RESIN 国立大学法人 岡山大学 2022-08-23 JP disclosed