Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 6/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | F12 | P00748 | 1/20 | 0.45 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1533447 | 0.92 | CYP1A2 (0.57) | CYP1A2ESR1ESR2HSD17B10HIF1A | |
| SCHEMBL1692369 | 0.89 | CYP1A2 (0.55) | CYP1A2ESR1ESR2HSD17B10HIF1A | |
| SCHEMBL29899643 | 0.89 | CYP1A2 (0.55) | CYP1A2ESR1ESR2HSD17B10HIF1A | |
| SCHEMBL670670 | 0.89 | CYP1A2 (0.52) | CYP1A2ESR1ESR2HSD17B10HIF1A | |
| SCHEMBL1170838 | 0.85 | CYP1A2 (0.65) | CYP1A2ESR1ESR2HSD17B10HIF1A | |
| SCHEMBL14809442 | 0.83 | HPRT1 (0.64) | CYP1A2HSD17B10HIF1ACYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL27891460 | 0.83 | CYP1A2 (0.62) | CYP1A2ESR1ESR2HSD17B10HIF1A | |
| SCHEMBL27289927 | 0.83 | HPRT1 (0.64) | CYP1A2HSD17B10HIF1ATSHRTDP1 | |
| SCHEMBL26132517 | 0.83 | HPRT1 (0.64) | CYP1A2HSD17B10HIF1ACYP3A4TSHR | |
| SCHEMBL12473664 | 0.83 | HPRT1 (0.64) | CYP1A2HSD17B10HIF1ATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140687-A1 | S1PR2 REGULATOR AND USE THEREOF | 北京昌平实验室 | 2024-07-04 | — | — | WO | disclosed |
| CN-118255830-A | S1PR2 modulators and uses thereof | 北京昌平实验室 | 2024-06-28 | — | — | CN | disclosed |
| CN-111116699-B | Cholic acid derivative and preparation method and medical application thereof | 江苏豪森药业集团有限公司 | 2023-02-28 | — | — | CN | disclosed |
| EP-3860643-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | St. Anna Kinderkrebsforschung (AT) | 2021-08-11 | — | — | EP | disclosed |
| EP-3860642-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | St. Anna Kinderkrebsforschung (AT) | 2021-08-11 | — | — | EP | disclosed |
| WO-2020070290-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | ST. ANNA KINDERKREBSFORSCHUNG (AT) | 2020-04-09 | — | — | WO | disclosed |
| WO-2020070289-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | ST. ANNA KINDERKREBSFORSCHUNG (AT) | 2020-04-09 | — | — | WO | disclosed |
| CN-104870612-B | Liquid crystal display and the liquid crystal media with vertical plane orientation | 默克专利股份有限公司 | 2017-09-12 | — | — | CN | disclosed |
| CN-107109056-A | Resin film formation composition and resin film | 日产化学工业株式会社 | 2017-08-29 | — | — | CN | disclosed |
| US-9676907-B2 | Methods and systems of graft polymerization on a functionalized substrate | ASPEN RESEARCH CORPORATION (US) | 2017-06-13 | — | — | US | disclosed |
| US-20160168331-A1 | METHODS AND SYSTEMS OF GRAFT POLYMERIZATION ON A FUNCTIONALIZED SUBSTRATE | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-06-16 | — | — | US | disclosed |
| US-9267009-B2 | Methods and systems of graft polymerization on a functionalized substrate | ASPEN RESEARCH CORPORATION (US) | 2016-02-23 | — | — | US | disclosed |
| US-20140296366-A1 | METHODS AND SYSTEMS OF GRAFT POLYMERIZATION ON A FUNCTIONALIZED SUBSTRATE | ASPEN RESEARCH CORPORATION (US) | 2014-10-02 | — | — | US | disclosed |
| CN-103906775-A | Methods and systems of graft polymerization on functionalized substrate | ASPEN RES CORP | 2014-07-02 | — | — | CN | disclosed |
| WO-2013033610-A1 | METHODS AND SYSTEMS OF GRAFT POLYMERIZATION ON A FUNCTIONALIZED SUBSTRATE | ASPEN RESEARCH CORPORATION (US) | 2013-03-07 | — | — | WO | disclosed |
| US-20050009733-A1 | Compositions of a cyclooxygenase-2 selective inhibitor and a potassium ion channel modulator for the treatment of central nervous system damage | PHARMACIA CORPORATION | 2005-01-13 | — | — | US | disclosed |
| EP-0320227-B1 | Method of preventing polymer-scale formation | SHINETSU CHEMICAL CO (JP) | 1994-09-07 | — | — | EP | disclosed |
| CN-1023324-C | Method of preventing polymer-scale formation | SHINETSU CHEMICAL CO (JP) | 1993-12-29 | — | — | CN | disclosed |
| US-4933399-A | COATING INSIDE OF VESSEL WITH A CATIONIC DYE, DRYING, COATING WITH AN ANIONIC OR AMPHOTERIC POLYMER OR A HYDROXYL-CONTAINING COMPOUND IN A SOLVENT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0320227-A2 | Method of preventing polymer-scale formation | Shin-Etsu Chemical Co., Ltd. (JP) | 1989-06-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009733-A1 | Compositions of a cyclooxygenase-2 selective inhibitor and a potassium ion channel modulator for the treatment of central nervous system damage | KCNJ2, KCNN2, KCNK2 | CYP1A2 1279/4885ESR1 4036/4885ESR2 2517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.