Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL29901719

CC(C)(C)OC(=O)N1CCC2(CCNC2)CC1.O=S(=O)(O)C(F)(F)F

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 10/20 0.39
USP2 O75604 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ACACB O00763 2/20 0.36
RORC P51449 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL484585 0.89 USP2 (0.46) GPR119USP2SMN1; SMN2ACACB
Hydrochloric Acid SCHEMBL896891 0.88 USP2 (0.45) GPR119USP2SMN1; SMN2ACACB
SCHEMBL30684021 0.81 CYP11B2 (0.45) USP2SMN1; SMN2ACACB
SCHEMBL29427773 0.81 CYP11B2 (0.45) USP2SMN1; SMN2ACACB
SCHEMBL617801 0.81 CYP11B2 (0.45) USP2SMN1; SMN2ACACB
SCHEMBL485160 0.81 USP2 (0.44) GPR119USP2SMN1; SMN2ACACB
SCHEMBL118654 0.81 CYP1A2 (0.50) GPR119USP2SMN1; SMN2ACACB
Hydrochloric Acid SCHEMBL993329 0.80 TSHR (0.44) USP2SMN1; SMN2ACACB
Hydrochloric Acid SCHEMBL15378006 0.80 USP2 (0.43) GPR119USP2SMN1; SMN2ACACB
Trifluoroacetic Acid SCHEMBL15571773 0.80 CYP1A2 (0.44) GPR119USP2SMN1; SMN2ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115028644-A SOS1 inhibitor heterocyclic compounds 首药控股(北京)股份有限公司 2022-09-09 CN disclosed