Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 3/20 | 0.62 |
| ▸ | YAP1 | P46937 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TNNI3K | Q59H18 | 5/20 | 0.45 |
| ▸ | IDH2 | P48735 | 4/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CCNH | P51946 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767446 | 1.00 | TEAD1 (0.62) | TEAD1YAP1MAPTTNNI3KIDH2 | |
| SCHEMBL20767405 | 0.90 | TEAD1 (0.77) | TEAD1YAP1MAPTTNNI3KTLR2 | |
| SCHEMBL29901814 | 0.90 | TEAD1 (0.77) | TEAD1YAP1MAPTTNNI3KTLR2 | |
| SCHEMBL20766513 | 0.88 | TEAD1 (0.80) | TEAD1YAP1MAPTTNNI3KIDH2 | |
| SCHEMBL20766734 | 0.84 | TEAD1 (0.60) | TEAD1YAP1MAPTTNNI3KIDH2 | |
| SCHEMBL29901824 | 0.84 | TEAD1 (0.60) | TEAD1YAP1MAPTTNNI3KIDH2 | |
| SCHEMBL20767258 | 0.79 | TEAD1 (0.85) | TEAD1YAP1MAPTTNNI3KIDH2 | |
| SCHEMBL25790239 | 0.78 | TEAD1 (0.54) | TEAD1YAP1MAPTTNNI3KIDH2 | |
| SCHEMBL29901821 | 0.77 | MAPT (0.55) | TEAD1YAP1MAPTTNNI3KIDH2 | |
| SCHEMBL20779791 | 0.77 | MAPT (0.55) | TEAD1YAP1MAPTTNNI3KIDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111542315-B | Benzosulfonyl compounds | 维瓦斯治疗公司 | 2023-05-12 | — | — | CN | disclosed |
| EP-3691623-B1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS INC (US) | 2022-10-05 | — | — | EP | disclosed |