Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 2/20 | 0.64 |
| ▸ | YAP1 | P46937 | 1/20 | 0.64 |
| ▸ | TNNI3K | Q59H18 | 6/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | CCR9 | P51686 | 1/20 | 0.36 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.36 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20766874 | 1.00 | TEAD1 (0.64) | TEAD1YAP1TNNI3KALDH3A1MAPT | |
| SCHEMBL25789977 | 0.92 | TEAD1 (0.55) | TEAD1YAP1TNNI3KALDH3A1MAPT | |
| SCHEMBL20766428 | 0.90 | TEAD1 (0.52) | TEAD1YAP1TNNI3KMAPTMEN1 | |
| SCHEMBL29901803 | 0.90 | TEAD1 (0.52) | TEAD1YAP1TNNI3KMAPTMEN1 | |
| SCHEMBL20766875 | 0.89 | ALDH3A1 (0.54) | TEAD1YAP1TNNI3KALDH3A1 | |
| SCHEMBL20779781 | 0.89 | MAPT (0.53) | TEAD1YAP1TNNI3KMAPTMEN1 | |
| SCHEMBL29901787 | 0.89 | MAPT (0.53) | TEAD1YAP1TNNI3KMAPTMEN1 | |
| SCHEMBL20779643 | 0.88 | TEAD1 (0.59) | TEAD1YAP1TNNI3KALDH3A1MAPT | |
| SCHEMBL29901827 | 0.87 | TEAD1 (0.49) | TEAD1YAP1TNNI3KALDH3A1MAPK1 | |
| SCHEMBL20766297 | 0.87 | TEAD1 (0.49) | TEAD1YAP1TNNI3KALDH3A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111542315-B | Benzosulfonyl compounds | 维瓦斯治疗公司 | 2023-05-12 | — | — | CN | disclosed |
| EP-3691623-B1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS INC (US) | 2022-10-05 | — | — | EP | disclosed |