Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 5/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10649682 | 0.88 | LMNA (0.68) | LMNARECQLKMT2AALDH1A1RAB9A | |
| SCHEMBL29902834 | 0.88 | LMNA (0.68) | LMNARECQLKMT2AALDH1A1RAB9A | |
| SCHEMBL29902852 | 0.86 | LMNA (0.66) | LMNARECQLKMT2AALDH1A1RAB9A | |
| SCHEMBL10648834 | 0.86 | LMNA (0.66) | LMNARECQLKMT2AALDH1A1RAB9A | |
| SCHEMBL10648953 | 0.85 | LMNA (0.64) | LMNARECQLKMT2AALDH1A1RAB9A | |
| SCHEMBL10651238 | 0.85 | LMNA (0.71) | LMNARECQLKMT2AALDH1A1RAB9A | |
| SCHEMBL10645963 | 0.84 | LMNA (0.63) | LMNARECQLKMT2AALDH1A1RAB9A | |
| SCHEMBL10649528 | 0.84 | LMNA (0.63) | LMNARECQLKMT2AALDH1A1RAB9A | |
| SCHEMBL10652188 | 0.83 | LMNA (0.69) | LMNARECQLKMT2AALDH1A1RAB9A | |
| SCHEMBL4497419 | 0.83 | LMNA (0.57) | LMNARECQLKMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808056-B | Dopamine D 2 Receptor selective agonists and their use in the treatment of disease | 中国科学院分子细胞科学卓越创新中心 | 2022-08-23 | — | — | CN | disclosed |