Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20404677 | 0.77 | IP6K1 (0.43) | ACVR1IP6K1TGFBR1 | |
| SCHEMBL10673703 | 0.76 | DPP4 (0.49) | DPP4DPP8ADORA2B | |
| SCHEMBL30430122 | 0.75 | DPP4 (0.35) | DPP4DPP8ADORA2B | |
| SCHEMBL4724897 | 0.73 | DPP4 (0.50) | DPP4DPP8FGFR1ADORA2B | |
| SCHEMBL24686841 | 0.72 | DPP4 (0.41) | DPP4DPP8FGFR1ACVR1DRD2 | |
| SCHEMBL1013519 | 0.72 | ALDH1A1 (0.50) | DPP4DPP8FGFR1 | |
| SCHEMBL8050564 | 0.72 | FGFR1 (0.56) | DPP4DPP8FGFR1DRD2DRD3 | |
| SCHEMBL16140228 | 0.72 | DPP4 (0.43) | DPP4DPP8FGFR1DRD2DRD3 | |
| SCHEMBL21187468 | 0.72 | DPP4 (0.51) | DPP4DPP8FGFR1 | |
| SCHEMBL15268278 | 0.72 | DPP4 (0.41) | DPP4DPP8FGFR1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077316-A1 | BENZIMIDAZOLE DERIVATIVES | Pfizer Inc. (US) | 2022-10-26 | — | — | EP | disclosed |