Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339451 | 1.00 | GAA (0.58) | GAAALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL20339628 | 0.90 | KMT2A (0.55) | GAAALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL29902966 | 0.90 | KMT2A (0.55) | GAAALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL20355814 | 0.86 | GAA (0.50) | GAAALDH1A1KDM4EKMT2AMEN1 | |
| Dodecanoate SCHEMBL7192361 | 0.85 | GAA (0.60) | GAAALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL14292042 | 0.83 | HDAC3 (0.68) | GAAKMT2AMEN1HDAC3HDAC4 | |
| SCHEMBL20339548 | 0.82 | KDM4E (0.51) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL29902945 | 0.82 | KDM4E (0.51) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL27466426 | 0.81 | MEN1 (0.51) | GAAALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL7522101 | 0.81 | GAA (0.66) | GAAALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167926-B | Poly-ADP ribose polymerase (PARP) inhibitors | 米托布里奇公司 | 2022-09-13 | — | — | CN | disclosed |