Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339628 | 1.00 | KMT2A (0.55) | KMT2AGAALMNAL3MBTL1MEN1 | |
| SCHEMBL29902900 | 0.90 | GAA (0.58) | KMT2AGAALMNAL3MBTL1MEN1 | |
| SCHEMBL20339451 | 0.90 | GAA (0.58) | KMT2AGAALMNAL3MBTL1MEN1 | |
| SCHEMBL20339581 | 0.82 | MAPK1 (0.51) | KMT2AL3MBTL1ALDH1A1KDM4ETP53 | |
| SCHEMBL29903006 | 0.82 | MAPK1 (0.51) | KMT2AL3MBTL1ALDH1A1KDM4ETP53 | |
| SCHEMBL13010627 | 0.81 | KMT2A (0.72) | KMT2AGAALMNAL3MBTL1MEN1 | |
| SCHEMBL15575684 | 0.80 | L3MBTL1 (0.57) | KMT2ALMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL29902911 | 0.80 | L3MBTL1 (0.57) | KMT2ALMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL14292042 | 0.78 | HDAC3 (0.68) | KMT2AGAALMNAMEN1HDAC3 | |
| SCHEMBL4361320 | 0.78 | PTPN1 (0.49) | KMT2AGAALMNAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167926-B | Poly-ADP ribose polymerase (PARP) inhibitors | 米托布里奇公司 | 2022-09-13 | — | — | CN | disclosed |