SCHEMBL2990301

SCHEMBL2990301

COC(=O)CCP(C)(C)=O

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.57
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 3/20 0.41
CA12 O43570 2/20 0.41
CA14 Q9ULX7 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 3/20 0.40
HSD17B10 Q99714 2/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
RECQL P46063 1/20 0.37
POLB P06746 1/20 0.35
TET2 Q6N021 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2397991 0.83 TSHR (0.55) TSHRKMT2AMEN1LMNACA12
SCHEMBL11811797 0.82 TSHR (0.60) TSHRKMT2AMEN1LMNACA12
SCHEMBL2984744 0.81 TSHR (0.52) TSHRKMT2AMEN1LMNACA12
SCHEMBL2460916 0.80 TSHR (0.61) TSHRKMT2AMEN1LMNACA12
SCHEMBL23829725 0.80 TSHR (0.57) TSHRKMT2AMEN1LMNACA12
SCHEMBL816663 0.78 TSHR (0.55) TSHRKMT2AMEN1LMNACA12
SCHEMBL2992989 0.76 TSHR (0.52) TSHRKMT2AMEN1LMNACA12
SCHEMBL1108185 0.76 CYP1A2 (0.48) TSHRKMT2ALMNAALDH1A1HSD17B10
SCHEMBL11490274 0.76 TSHR (0.52) TSHRKMT2AMEN1LMNACA12
SCHEMBL10937402 0.76 TSHR (0.52) TSHRKMT2AMEN1LMNACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2237358-B1 Nonaqueous electrolyte battery MITSUBISHI CHEM CORP (JP) 2015-08-12 EP disclosed
US-8962192-B2 Nonaqueous electrolytic solution and nonaqueous electrolyte battery MITSUBISHI CHEMICAL CORPORATION (JP) 2015-02-24 US disclosed
US-8574757-B2 Nonaqueous electrolytic solution and nonaqueous electrolyte battery MITSUBISHI CHEMICAL CORPORATION (JP) 2013-11-05 US disclosed
EP-2128923-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY MITSUBISHI CHEM CORP (JP) 2013-01-16 EP disclosed
US-20120264011-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-10-18 US disclosed
US-20120156557-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-06-21 US disclosed
EP-2237358-A1 Nonaqueous electrolyte battery MITSUBISHI CHEMICAL CORPORATION (JP) 2010-10-06 EP disclosed
US-20100035147-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2010-02-11 US disclosed
EP-2128923-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY Mitsubishi Chemical Corporation (JP) 2009-12-02 EP disclosed
EP-0388910-B1 Procedure for the preparation of phosphino derivatives HOECHST SCHERING AGREVO GMBH (DE) 1994-08-31 EP disclosed
US-5166385-A Process for the preparation of phosphino compounds HOECHST AKTIENGESELLSCHAFT (DE) 1992-11-24 US disclosed
EP-0388910-A2 Procedure for the preparation of phosphino derivatives Hoechst Schering AgrEvo GmbH (DE) 1990-09-26 EP disclosed