Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23829725 | 0.81 | TSHR (0.57) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL2460916 | 0.81 | TSHR (0.61) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL816663 | 0.79 | TSHR (0.55) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL2397991 | 0.79 | TSHR (0.55) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL8622494 | 0.79 | ALDH1A1 (0.41) | TSHRKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL11811797 | 0.78 | TSHR (0.60) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL2984744 | 0.77 | TSHR (0.52) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL8564916 | 0.76 | POLB (0.44) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL2990301 | 0.76 | TSHR (0.57) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL23832898 | 0.76 | MAPK1 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4045496-A | Process for the hydroxylation of phenols and phenol ethers in the nucleus | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-30 | — | — | US | claimed |
| US-4214105-A | Process for the hydroxylation of phenol | BAYER AKTIENGESELLSCHAFT (DE) | 1980-07-22 | — | — | US | disclosed |
| US-4174460-A | Process for the hydroxylation of phenols and phenol ethers in the nucleus | BAYER AKTIENGESELLSCHAFT (DE) | 1979-11-13 | — | — | US | disclosed |
| US-4053523-A | PROCESS FOR THE HYDROXYLATION OF PHENOL | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |
| US-4045496-A | Process for the hydroxylation of phenols and phenol ethers in the nucleus | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-30 | — | — | US | disclosed |