Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26978071 | 1.00 | LMNA (0.41) | LMNAMAPTALDH1A1PIK3CACYP1A2 | |
| SCHEMBL26977788 | 0.88 | LMNA (0.40) | LMNAMAPTALDH1A1PIK3CACYP1A2 | |
| SCHEMBL30559715 | 0.85 | LMNA (0.45) | LMNAMAPTALDH1A1PIK3CACYP1A2 | |
| SCHEMBL26977468 | 0.84 | APP (0.45) | LMNAMAPTALDH1A1PIK3CACYP1A2 | |
| SCHEMBL26977362 | 0.84 | LMNA (0.44) | LMNAMAPTALDH1A1PIK3CACYP1A2 | |
| SCHEMBL26978014 | 0.82 | LMNA (0.42) | LMNAMAPTALDH1A1PIK3CACYP1A2 | |
| SCHEMBL29903790 | 0.81 | LMNA (0.41) | LMNAMAPTALDH1A1PIK3CACYP1A2 | |
| SCHEMBL29903831 | 0.81 | LMNA (0.41) | LMNAMAPTALDH1A1PIK3CACYP1A2 | |
| SCHEMBL26977760 | 0.81 | LMNA (0.41) | LMNAMAPTALDH1A1PIK3CACYP1A2 | |
| SCHEMBL26977974 | 0.81 | LMNA (0.41) | LMNAMAPTALDH1A1PIK3CACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025243044-A1 | COMPOUNDS | Pheno Therapeutics Limited (GB) | 2025-11-27 | — | — | WO | disclosed |
| EP-4298092-A1 | NOVEL PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2024-01-03 | — | — | EP | disclosed |
| CN-116829550-A | Pyrimidine-2-ylsulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2022180136-A1 | NOVEL PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2022-09-01 | — | — | WO | disclosed |