Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27415952 | 1.00 | AMY1A (0.46) | AMY1APTGS1PTGS2USP7PRKAB2 | |
| SCHEMBL27415921 | 0.84 | RPS6KA3 (0.46) | PTGS2USP7NPC1RAB9AMEN1 | |
| SCHEMBL10340365 | 0.80 | AMY1A (0.50) | AMY1APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL17436330 | 0.77 | CLK1 (0.47) | AMY1APTGS1PTGS2USP7PRKAB2 | |
| SCHEMBL12987241 | 0.75 | AMY1A (0.50) | AMY1APTGS1PTGS2NPC1RAB9A | |
| SCHEMBL14637411 | 0.74 | AMY1A (0.43) | AMY1APTGS1PTGS2USP7PRKAB2 | |
| SCHEMBL19387237 | 0.72 | AMY1A (0.46) | AMY1APTGS1PTGS2USP7PRKAB2 | |
| SCHEMBL15832088 | 0.72 | KCNQ3 (0.45) | NPC1RAB9A | |
| SCHEMBL8430167 | 0.72 | KDM1A (0.55) | AMY1ANPC1RAB9ACYP17A1CYP11B1 | |
| SCHEMBL22537008 | 0.72 | NPC1 (0.55) | AMY1ANPC1RAB9AGRM2ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212818-A1 | 1,2,4-TRIAZOLO[4,3-A]PYRIDINE DERIVATIVES AS NEGATIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR 2 | VANDERBILT UNIVERSITY (US) | 2022-10-06 | — | — | WO | disclosed |