Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.53 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26906752 | 1.00 | EGFR (0.53) | EGFRALKLRRK2 | |
| SCHEMBL26906679 | 0.96 | EGFR (0.51) | EGFRLRRK2 | |
| SCHEMBL30659887 | 0.96 | EGFR (0.51) | EGFRLRRK2 | |
| SCHEMBL26906747 | 0.93 | EGFR (0.57) | EGFRALK | |
| SCHEMBL26906748 | 0.91 | EGFR (0.52) | EGFRLRRK2 | |
| SCHEMBL26906831 | 0.91 | EGFR (0.57) | EGFR | |
| SCHEMBL26906555 | 0.90 | EGFR (0.61) | EGFRALKLRRK2 | |
| SCHEMBL30860343 | 0.90 | EGFR (0.61) | EGFRALKLRRK2 | |
| SCHEMBL30860310 | 0.90 | EGFR (0.54) | EGFRALKLRRK2 | |
| SCHEMBL26906576 | 0.90 | EGFR (0.54) | EGFRALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022211573-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2022-10-06 | — | — | WO | claimed |
| EP-4286376-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | Therapex Co., Ltd. (KR) | 2023-12-06 | — | — | EP | disclosed |
| WO-2022211573-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2022-10-06 | — | — | WO | disclosed |