Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26906679 | 1.00 | EGFR (0.51) | EGFRLRRK2 | |
| SCHEMBL29904625 | 0.96 | EGFR (0.53) | EGFRLRRK2 | |
| SCHEMBL26906752 | 0.96 | EGFR (0.53) | EGFRLRRK2 | |
| SCHEMBL26906748 | 0.95 | EGFR (0.52) | EGFRLRRK2 | |
| SCHEMBL26906831 | 0.95 | EGFR (0.57) | EGFR | |
| SCHEMBL26906576 | 0.94 | EGFR (0.54) | EGFR | |
| SCHEMBL26906596 | 0.93 | EGFR (0.55) | EGFR | |
| SCHEMBL26906833 | 0.90 | EGFR (0.63) | EGFR | |
| SCHEMBL26906747 | 0.90 | EGFR (0.57) | EGFR | |
| SCHEMBL26907010 | 0.89 | EGFR (0.58) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120424-A | Pyrimidine derivatives having protein kinase inhibitory activity and therapeutic combinations comprising the same | 泰拉佩克斯有限公司 | 2023-11-24 | — | — | CN | disclosed |