Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 11/20 | 0.64 |
| ▸ | F2 | P00734 | 10/20 | 0.64 |
| ▸ | KLK1 | P06870 | 4/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL18040012 | 0.94 | KLKB1 (0.58) | KLKB1F2KLK1 | |
| Hydrochloric Acid SCHEMBL18040015 | 0.90 | F2 (0.68) | KLKB1F2KLK1 | |
| SCHEMBL29905427 | 0.85 | F2 (0.64) | KLKB1F2 | |
| SCHEMBL29905444 | 0.84 | F2 (0.70) | KLKB1F2KLK1 | |
| Hydrochloric Acid SCHEMBL18040037 | 0.84 | F2 (0.69) | KLKB1F2KLK1 | |
| SCHEMBL18040060 | 0.83 | KLKB1 (0.57) | KLKB1F2KLK1 | |
| SCHEMBL29905316 | 0.83 | KLKB1 (0.63) | KLKB1F2KLK1 | |
| SCHEMBL18351681 | 0.82 | KLKB1 (0.59) | KLKB1F2KLK1 | |
| SCHEMBL18040041 | 0.82 | F2 (0.56) | KLKB1F2KLK1 | |
| SCHEMBL20473866 | 0.81 | F2 (0.83) | KLKB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3261639-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON INT CORPORATION (US) | 2022-08-24 | — | — | EP | claimed |
| EP-3261639-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON INT CORPORATION (US) | 2022-08-24 | — | — | EP | disclosed |