Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.70 |
| ▸ | KLKB1 | P03952 | 12/20 | 0.61 |
| ▸ | KLK1 | P06870 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18040037 | 0.99 | F2 (0.69) | F2KLKB1KLK1 | |
| Hydrochloric Acid SCHEMBL18040015 | 0.85 | F2 (0.68) | F2KLKB1KLK1 | |
| SCHEMBL29905227 | 0.84 | KLKB1 (0.64) | F2KLKB1KLK1 | |
| SCHEMBL18039902 | 0.82 | F2 (1.00) | F2KLKB1 | |
| SCHEMBL29905184 | 0.82 | F2 (0.69) | F2KLKB1KLK1 | |
| SCHEMBL29905946 | 0.80 | F2 (0.77) | F2KLKB1KLK1 | |
| SCHEMBL20473859 | 0.80 | F2 (0.85) | F2KLKB1 | |
| Hydrochloric Acid SCHEMBL18039935 | 0.80 | F2 (0.76) | F2KLKB1KLK1 | |
| Hydrochloric Acid SCHEMBL29905263 | 0.80 | F2 (0.76) | F2KLKB1KLK1 | |
| SCHEMBL18351681 | 0.79 | KLKB1 (0.59) | F2KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3261639-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON INT CORPORATION (US) | 2022-08-24 | — | — | EP | claimed |
| EP-3261639-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON INT CORPORATION (US) | 2022-08-24 | — | — | EP | disclosed |