Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.47 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879571 | 0.84 | NFE2L2 (0.52) | KDM1ANFE2L2HDAC1HDAC6HDAC5 | |
| SCHEMBL2879570 | 0.84 | NFE2L2 (0.52) | KDM1ANFE2L2HDAC1HDAC6HDAC5 | |
| SCHEMBL31705885 | 0.81 | MAPT (0.52) | KDM1AHDAC1HDAC6IP6K1 | |
| SCHEMBL18112564 | 0.81 | MAPT (0.52) | KDM1AHDAC1HDAC6IP6K1 | |
| SCHEMBL16749603 | 0.81 | MAPT (0.52) | KDM1AHDAC1HDAC6IP6K1 | |
| SCHEMBL4056984 | 0.81 | PTGS1 (0.53) | KDM1ANFE2L2HDAC1HDAC6HDAC5 | |
| SCHEMBL4056989 | 0.81 | PTGS1 (0.53) | KDM1ANFE2L2HDAC1HDAC6HDAC5 | |
| SCHEMBL29905803 | 0.80 | KDM1A (0.54) | KDM1ANFE2L2HDAC1HDAC6PTGS1 | |
| SCHEMBL2319434 | 0.79 | KDM1A (0.53) | KDM1ANFE2L2HDAC1HDAC6GRM4 | |
| SCHEMBL29905760 | 0.79 | KDM1A (0.53) | KDM1ANFE2L2HDAC1HDAC6GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4054717-A1 | METAL COMPLEXES BEARING BISSTYRYL-BIPYRIDINE LIGAND AND THEIR USE AS PHOTOSENSITIZER AGENT IN ONE AND TWO-PHOTON PHOTODYNAMIC THERAPY | Paris Sciences et Lettres (FR) | 2022-09-14 | — | — | EP | disclosed |