Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.80 |
| ▸ | ATP4A | P20648 | 10/20 | 0.66 |
| ▸ | ATP4B | P51164 | 10/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | PPARG | P37231 | 1/20 | 0.65 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27152396 | 1.00 | MEN1 (0.80) | MEN1KMT2AATP4AATP4BMAPT | |
| SCHEMBL1800635 | 0.79 | MEN1 (1.00) | MEN1KMT2AATP4AATP4BMAPT | |
| SCHEMBL27136074 | 0.78 | MEN1 (0.58) | MEN1KMT2AATP4AATP4BMAPT | |
| SCHEMBL29906057 | 0.78 | MEN1 (0.58) | MEN1KMT2AATP4AATP4BMAPT | |
| SCHEMBL23610340 | 0.74 | MEN1 (0.55) | MEN1KMT2AMAPTKDM4ERAB9A | |
| SCHEMBL3130593 | 0.73 | MAPT (0.61) | MEN1KMT2AMAPTKDM4ERAB9A | |
| SCHEMBL5331147 | 0.73 | MEN1 (0.57) | MEN1KMT2AMAPTKDM4ERAB9A | |
| SCHEMBL31512490 | 0.73 | MEN1 (0.57) | MEN1KMT2AMAPTKDM4ERAB9A | |
| SCHEMBL30693723 | 0.73 | ATP4A (0.49) | MEN1KMT2AATP4AATP4BMAPT | |
| SCHEMBL1689568 | 0.71 | MPL (0.63) | MEN1KMT2AMAPTKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4326262-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | Fundació Privada Institut d'Investigació Oncològica de Vall Hebron (ES) | 2024-02-28 | — | — | EP | disclosed |
| CN-117320715-A | Compounds for the treatment of hyperproliferative diseases | 瓦尔希伯伦私人肿瘤研究基金会 | 2023-12-29 | — | — | CN | disclosed |
| WO-2022223704-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | FUNDACIÓ PRIVADA INSTITUT D'INVESTIGACIÓ ONCOLÒGICA DE VALL HEBRON (ES) | 2022-10-27 | — | — | WO | disclosed |