Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL842908 | 1.00 | HSD17B10 (0.60) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27796780 | 0.86 | HSD17B10 (0.56) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL508763 | 0.85 | HSD17B10 (0.60) | HSD17B10LMNASMN1; SMN2ALDH1A1VCAM1 | |
| SCHEMBL29672035 | 0.85 | HSD17B10 (0.60) | HSD17B10LMNASMN1; SMN2ALDH1A1VCAM1 | |
| SCHEMBL863249 | 0.83 | HSD17B10 (0.62) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL13241715 | 0.83 | HSD17B10 (0.62) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL260864 | 0.82 | CYP1A2 (0.47) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29368452 | 0.82 | CYP1A2 (0.47) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2182437 | 0.81 | HSD17B10 (0.60) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8262558 | 0.81 | HSD17B10 (0.60) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373809-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | Novartis AG (CH) | 2024-05-29 | — | — | EP | disclosed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-116514728-A | Quinazoline derivative and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-115925711-A | Substituted pyrazolo [1,5-a ] pyrimidines and their use in treating medical disorders | BIAL研发投资股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-109562111-B | CK2 inhibitors, compositions and methods thereof | 北极星药业股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |
| CN-107001379-B | Substituted pyrazolo [1,5-a ] pyrimidines and their use in the treatment of medical disorders | BIAL研发投资股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| WO-2022184904-A1 | PHOTOREDOX RADICAL BENZYLATION PROCESS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2022-09-09 | — | — | WO | disclosed |