Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672035 | 1.00 | HSD17B10 (0.60) | HSD17B10KMT2AALDH1A1VCAM1PDE7A | |
| SCHEMBL30001251 | 0.86 | HSD17B10 (0.56) | HSD17B10KMT2AALDH1A1VCAM1PDE7A | |
| SCHEMBL2595412 | 0.86 | HSD17B10 (0.56) | HSD17B10KMT2AALDH1A1VCAM1PDE7A | |
| SCHEMBL29906404 | 0.85 | HSD17B10 (0.60) | HSD17B10KMT2AALDH1A1VCAM1TDP1 | |
| SCHEMBL842908 | 0.85 | HSD17B10 (0.60) | HSD17B10KMT2AALDH1A1VCAM1TDP1 | |
| SCHEMBL8703100 | 0.83 | HSD17B10 (0.46) | HSD17B10KMT2AALDH1A1VCAM1PDE7A | |
| SCHEMBL136817 | 0.83 | CYP1A2 (0.62) | KMT2AALDH1A1TDP1CYP1A2LMNA | |
| SCHEMBL7786691 | 0.83 | HSD17B10 (0.62) | HSD17B10KMT2AALDH1A1VCAM1PDE7A | |
| SCHEMBL868877 | 0.83 | HSD17B10 (0.62) | HSD17B10KMT2AALDH1A1VCAM1PDE7A | |
| SCHEMBL2205749 | 0.83 | HSD17B10 (0.62) | HSD17B10KMT2AALDH1A1VCAM1PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250361232-A1 | SUBSTITUTED ACETYLENIC PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS KINASE INHIBITORS | TAKEDA PHARMACEUTICALS USA INC (US) | 2025-11-27 | — | — | US | disclosed |
| US-12398142-B2 | Abelson non-tyrosine kinase compounds for the treatment of neurodegenerative diseases | EMORY UNIVERSITY (US) | 2025-08-26 | — | — | US | disclosed |
| CN-114573567-B | Indazole cyclotriazole compound and preparation method and application thereof | 西安交通大学 | 2023-05-02 | — | — | CN | disclosed |
| US-20220177480-A1 | Abelson Non-Tyrosine Kinase Compounds for the Treatment of Neurodegenerative Diseases | UNIV EMORY (US) | 2022-06-09 | — | — | US | disclosed |
| US-20220177480-A1 | Abelson Non-Tyrosine Kinase Compounds for the Treatment of Neurodegenerative Diseases | UNIV EMORY (US) | 2022-06-09 | — | — | US | disclosed |
| CN-114573567-A | Indazole cyclic triazole compound and preparation method and application thereof | 西安交通大学 | 2022-06-03 | — | — | CN | disclosed |
| US-20220081440-A1 | SUBSTITUTED ACETYLENIC PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS KINASE INHIBITORS | TAKEDA PHARMACEUTICALS U.S.A., INC. | 2022-03-17 | — | — | US | disclosed |
| EP-3747441-A1 | BICYCLIC HETEROARYL COMPOUNDS | ARIAD Pharmaceuticals, Inc. (US) | 2020-12-09 | — | — | EP | disclosed |
| CN-112010789-A | Vinyl sulfonamide or vinyl amide compounds, and preparation method and application thereof | 中国科学院上海药物研究所 | 2020-12-01 | — | — | CN | disclosed |
| WO-2020214999-A1 | ABELSON NON-TYROSINE KINASE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | EMORY UNIVERSITY (US) | 2020-10-22 | — | — | WO | disclosed |
| EP-1117659-B1 | SUBSTITUTED 3-CYANOQUINOLINES AS PROTEIN TYROSINE KINASES INHIBITORS | WYETH CORP (US) | 2003-12-03 | — | — | EP | disclosed |
| WO-2003040108-A1 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | ASTRAZENECA AB (SE) | 2003-05-15 | — | — | WO | disclosed |
| US-6288082-B1 | COMPOUNDS SUCH AS 6,7-DIETHOXY-4-(INDAN-5-YLAMINO) -QUINOLINE-3-CARBONITRILE USED AS ANTINEOPLASTIC AGENTS AND IN THE TREATMENT OF POLYCYCSTIC KIDNEY DISEASE | AMERICAN CYANAMID COMPANY | 2001-09-11 | — | — | US | disclosed |
| EP-1117659-A1 | SUBSTITUTED 3-CYANOQUINOLINES AS PROTEIN TYROSINE KINASES INHIBITORS | American Cyanamid Company (US) | 2001-07-25 | — | — | EP | disclosed |
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| CN-1265661-A | N-acylamino acid amide compounds and intermediates for preparation thereof | UBE INDUSTRIES (JP) | 2000-09-06 | — | — | CN | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |
| WO-2000018761-A1 | SUBSTITUTED 3-CYANOQUINOLINES AS PROTEIN TYROSINE KINASES INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 2000-04-06 | — | — | WO | disclosed |
| US-4436751-A | Nitrobenzyl monates antibacterial compounds | BEECHAM GROUP LIMITED (GB) | 1984-03-13 | — | — | US | disclosed |
| EP-0055616-A1 | Antibacterial compounds | BEECHAM GROUP PLC (GB) | 1982-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220081440-A1 | SUBSTITUTED ACETYLENIC PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS KINASE INHIBITORS | MAP4K2, MAP3K19, MAP3K1 | HSD17B10 3108/4885KMT2A 1337/4885ALDH1A1 980/4885 |
| US-20220177480-A1 | Abelson Non-Tyrosine Kinase Compounds for the Treatment of Neurodegenerative Diseases | ABL2, ABL1, FYN | HSD17B10 4283/4885KMT2A 784/4885ALDH1A1 3669/4885 |
| US-20250361232-A1 | SUBSTITUTED ACETYLENIC PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS KINASE INHIBITORS | MAP4K2, MAP3K19, MAP3K1 | HSD17B10 3108/4885KMT2A 1337/4885ALDH1A1 980/4885 |
| US-12398142-B2 | Abelson non-tyrosine kinase compounds for the treatment of neurodegenerative diseases | ABL2, ABL1, FYN | HSD17B10 4283/4885KMT2A 784/4885ALDH1A1 3669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.