SCHEMBL2990646

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2986842	0.91	SERPINE1 (0.51)	SERPINE1MAPTSMN1; SMN2SRD5A1SRD5A2
	SCHEMBL2992751	0.87	SERPINE1 (0.57)	SERPINE1MAPTSMN1; SMN2SRD5A1SRD5A2
	SCHEMBL2990722	0.87	SERPINE1 (0.56)	SERPINE1MAPTSMN1; SMN2SRD5A1SRD5A2
	SCHEMBL12091779	0.82	SERPINE1 (0.53)	SERPINE1MAPTSRD5A1SRD5A2PTGER1
	SCHEMBL2996651	0.81	SERPINE1 (0.69)	SERPINE1MAPTSMN1; SMN2SRD5A1SRD5A2
	SCHEMBL2987677	0.79	SERPINE1 (0.63)	SERPINE1MAPTSMN1; SMN2SRD5A1SRD5A2
	SCHEMBL2995702	0.78	SERPINE1 (0.60)	SERPINE1MAPTSMN1; SMN2SRD5A1SRD5A2
	SCHEMBL2993855	0.78	MAPT (0.42)	MAPTSMN1; SMN2PTGER1STIM1ORAI1
	SCHEMBL12092458	0.77	SERPINE1 (0.59)	SERPINE1MAPTSMN1; SMN2SRD5A1SRD5A2
	SCHEMBL2993810	0.76	SERPINE1 (0.60)	SERPINE1MAPTSMN1; SMN2SRD5A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.