Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 10/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
| ▸ | TUBB | P07437 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.33 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.33 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23210989 | 1.00 | BUB1 (0.35) | BUB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23210807 | 0.95 | BUB1 (0.34) | BUB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29907045 | 0.95 | BUB1 (0.34) | BUB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29008844 | 0.90 | BUB1 (0.35) | BUB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23211111 | 0.90 | BUB1 (0.33) | BUB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23210888 | 0.90 | BUB1 (0.35) | BUB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29907122 | 0.90 | BUB1 (0.35) | BUB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23210951 | 0.89 | GYS1 (0.35) | BUB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23210911 | 0.88 | BUB1 (0.34) | BUB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29008852 | 0.88 | BUB1 (0.36) | BUB1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045151-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2022-08-24 | — | — | EP | disclosed |