Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23236616 | 0.95 | ELANE (0.34) | PGK1NPC1RAB9AELANEMEN1 | |
| SCHEMBL30294194 | 0.95 | ELANE (0.34) | PGK1NPC1RAB9AELANEMEN1 | |
| SCHEMBL29907184 | 0.88 | EHMT2 (0.34) | PGK1NPC1RAB9AGAASHMT2 | |
| SCHEMBL23211031 | 0.84 | NPC1 (0.37) | NPC1RAB9AGAASHMT2CASP3 | |
| SCHEMBL30294191 | 0.82 | EHMT2 (0.37) | NPC1RAB9AGAAELANEMEN1 | |
| SCHEMBL23211124 | 0.82 | EHMT2 (0.37) | NPC1RAB9AGAAELANEMEN1 | |
| SCHEMBL23210861 | 0.81 | SHMT2 (0.38) | PGK1NPC1RAB9AGAASHMT2 | |
| SCHEMBL29907085 | 0.81 | SHMT2 (0.38) | PGK1NPC1RAB9AGAASHMT2 | |
| SCHEMBL23236625 | 0.78 | SUV39H2 (0.32) | NPC1RAB9ANR1H2SUV39H2MERTK | |
| SCHEMBL29907131 | 0.78 | SUV39H2 (0.32) | NPC1RAB9ANR1H2SUV39H2MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045151-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2022-08-24 | — | — | EP | disclosed |