Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | IL1RN | P18510 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2327414 | 1.00 | CYP1A2 (0.52) | CYP1A2PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL29385577 | 0.83 | CYP2A6 (0.52) | CYP1A2PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL1868979 | 0.83 | CYP2A6 (0.52) | CYP1A2PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL1662187 | 0.83 | CYP2A6 (0.52) | CYP1A2PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL14419537 | 0.80 | MEN1 (0.40) | CYP1A2PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL7913165 | 0.80 | CYP2A6 (0.44) | CYP1A2PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL9523617 | 0.78 | CYP1A2 (0.52) | CYP1A2CYP2A6MEN1USP2ALDH1A1 | |
| SCHEMBL17132727 | 0.77 | TRPA1 (0.49) | CYP1A2PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL25300354 | 0.74 | CYP1A2 (0.52) | CYP1A2CYP2A6MEN1USP2ALDH1A1 | |
| SCHEMBL9672282 | 0.74 | CYP1A2 (0.52) | CYP1A2CYP2A6MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769545-A | Tri-fused ring derivative-containing regulator, preparation method and application thereof | 上海枢境生物科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117751126-A | Oxaspiro derivative, preparation method and application thereof | 上海枢境生物科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-115835908-A | Bicyclic heterocycles as FGFR inhibitors | 因赛特公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-4045151-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2022-08-24 | — | — | EP | disclosed |