SCHEMBL2990732

SCHEMBL2990732

O=C(O)Cc1cccc(-c2ccccc2)c1CC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 2/20 0.52
PTGS1 P23219 2/20 0.50
FOLH1 Q04609 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
PTGDR2 Q9Y5Y4 1/20 0.49
DUSP3 P51452 1/20 0.49
PTPN5 P54829 1/20 0.49
PTPN11 Q06124 1/20 0.49
CTDSP1 Q9GZU7 1/20 0.49
KMT2A Q03164 1/20 0.49
PTGER1 P34995 2/20 0.48
PTGER4 P35408 2/20 0.48
PTGER3 P43115 2/20 0.48
PTGER2 P43116 2/20 0.48
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
ABCC4 O15439 1/20 0.46
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2392464 0.89 PTGDR2 (0.50) AKR1B1PTGS1FOLH1TDP1PTGDR2
SCHEMBL5381774 0.88 AKR1B1 (0.52) AKR1B1PTGS1FOLH1TDP1PTGDR2
SCHEMBL1919745 0.88 DPP4 (0.56) AKR1B1PTGS1FOLH1TDP1PTGDR2
SCHEMBL538512 0.84 KMT2A (0.60) AKR1B1PTGS1FOLH1TDP1PTGDR2
SCHEMBL28594606 0.82 KMT2A (0.58) AKR1B1PTGS1FOLH1TDP1PTGDR2
Hydrochloric Acid SCHEMBL11895689 0.82 KMT2A (0.58) AKR1B1PTGS1FOLH1TDP1PTGDR2
SCHEMBL29512995 0.82 KMT2A (0.58) AKR1B1PTGS1FOLH1TDP1PTGDR2
SCHEMBL27701716 0.82 KMT2A (0.58) AKR1B1PTGS1FOLH1TDP1PTGDR2
Ammonia Solution, Strong SCHEMBL27926479 0.82 KMT2A (0.58) AKR1B1PTGS1FOLH1TDP1PTGDR2
SCHEMBL28375198 0.82 FOLH1 (0.47) PTGS1FOLH1PTGDR2KMT2APTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021040440-A1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING NONALCOHOLIC STEATOHEPATITIS (NASH) (주)셀트리온 2021-03-04 WO claimed
JP-3634377-B2 2005-03-30 JP claimed
EP-0854731-A1 COPOLYMERIC MICELLE DRUG COMPOSITION AND METHOD FOR THE PREPARATION THEREOF Sam Yang Co., Ltd. (KR) 1998-07-29 EP claimed
WO-1997010849-A1 COPOLYMERIC MICELLE DRUG COMPOSITION AND METHOD FOR THE PREPARATION THEREOF SAM YANG CO., LTD. (KR) 1997-03-27 WO claimed
CN-116056889-A Laminate, image display member, method for manufacturing image display member, mobile electronic device, and method for manufacturing mobile electronic device 日东电工株式会社 2023-05-02 CN disclosed
CN-113165362-B Adhesive film, foldable device, and rollable device 日东电工株式会社 2023-04-14 CN disclosed
CN-114008156-B Protective film, foldable device and rollable device 日东电工株式会社 2022-11-15 CN disclosed
CN-114907787-A Adhesive sheet and optical member 日东电工株式会社 2022-08-16 CN disclosed
CN-114561159-A Surface protective film 日东电工株式会社 2022-05-31 CN disclosed
CN-114545531-A Protective film for polarizer, method for producing protective film for polarizer, and apparatus for producing protective film for polarizer 日东电工株式会社 2022-05-27 CN disclosed
CN-114340632-A Pharmaceutical composition for treating or preventing nonalcoholic steatohepatitis (NASH) 赛特瑞恩股份有限公司 2022-04-12 CN disclosed
WO-2022030152-A1 LAYERED BODY, IMAGE DISPLAY MEMBER AND MANUFACTURING METHOD THEREOF, AND MOBILE ELECTRONIC DEVICE AND MANUFACTURING METHOD THEREOF 日東電工株式会社 2022-02-10 WO disclosed
US-7787085-B2 Optical alignment method and liquid crystal display element JSR CORPORATION (JP) 2010-08-31 US disclosed
US-20080123046-A1 OPTICAL ALIGNMENT METHOD AND LIQUID CRYSTAL DISPLAY ELEMENT JSR CORPORATION (JP) 2008-05-29 US disclosed
US-20050259203-A1 Optical alignment method and liquid crystal display element JSR CORPORATION (JP) 2005-11-24 US disclosed
EP-1353217-A1 Optical alignment method and liquid crystal display element JSR Corporation (JP) 2003-10-15 EP disclosed
EP-0854731-B1 COPOLYMERIC MICELLE DRUG COMPOSITION AND METHOD FOR THE PREPARATION THEREOF SAM YANG CO (KR) 2003-01-22 EP disclosed
US-6224788-B1 AROMATIC UNSATURATED KETONE POLYMERS JSR CORPORATION (JP) 2001-05-01 US disclosed
EP-0854731-A1 COPOLYMERIC MICELLE DRUG COMPOSITION AND METHOD FOR THE PREPARATION THEREOF Sam Yang Co., Ltd. (KR) 1998-07-29 EP disclosed
WO-1997010849-A1 COPOLYMERIC MICELLE DRUG COMPOSITION AND METHOD FOR THE PREPARATION THEREOF SAM YANG CO., LTD. (KR) 1997-03-27 WO disclosed