SCHEMBL29907421

SCHEMBL29907421

CC(C)(O)c1ccc(NC(=O)c2ccnn(-c3ccccc3OCC(F)(F)F)c2=O)c(F)c1

nearest known ligand 0.78

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
UGCG Q16739 6/20 0.78
SCN9A Q15858 2/20 0.47
MRGPRX1 Q96LB2 3/20 0.43
MET P08581 5/20 0.42
GSK3A P49840 1/20 0.41
LCLAT1 Q6UWP7 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
AXL P30530 1/20 0.38
TYRO3 Q06418 1/20 0.38
MERTK Q12866 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29907412 0.89 UGCG (0.62) UGCGSCN9AMETLCLAT1AXL
SCHEMBL24464270 0.89 UGCG (0.62) UGCGSCN9AMETLCLAT1AXL
SCHEMBL29907426 0.88 UGCG (1.00) UGCGSCN9AMETGSK3ALCLAT1
SCHEMBL29907472 0.85 UGCG (0.79) UGCGSCN9AMETGSK3AAXL
SCHEMBL29907369 0.82 UGCG (0.62) UGCGSCN9AMETLCLAT1
SCHEMBL29907486 0.81 UGCG (0.54) UGCGSCN9AMETLCLAT1AXL
SCHEMBL29907497 0.81 UGCG (0.81) UGCGSCN9AMETGSK3AKDM4E
SCHEMBL29907394 0.80 UGCG (0.82) UGCGMETGSK3ALCLAT1KDM4E
SCHEMBL29907579 0.77 UGCG (0.81) UGCGMETAXLTYRO3MERTK
SCHEMBL29907634 0.77 UGCG (0.76) UGCGMETGSK3AKDM4EAXL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220289679-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220289679-A1 HETEROCYCLIC COMPOUND GBA1, GBA2, GALC UGCG 10/4885SCN9A 1952/4885MRGPRX1 2038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.