SCHEMBL29907472

SCHEMBL29907472

CC(C)(O)c1ccc(NC(=O)c2ccnn(-c3ccccc3OCC(F)(F)F)c2=O)nc1

nearest known ligand 0.79

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
UGCG Q16739 7/20 0.79
SCN9A Q15858 5/20 0.47
AXL P30530 2/20 0.42
MERTK Q12866 2/20 0.42
MET P08581 1/20 0.42
GSK3A P49840 1/20 0.40
F10 P00742 1/20 0.39
TYRO3 Q06418 1/20 0.38
PTGES O14684 1/20 0.38
GAA P10253 1/20 0.38
TRPV1 Q8NER1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29907372 0.89 UGCG (0.63) UGCGSCN9AAXLMERTKMET
SCHEMBL29907426 0.89 UGCG (1.00) UGCGSCN9AAXLMERTKMET
SCHEMBL29907428 0.86 UGCG (0.60) UGCGSCN9AAXLMERTKMET
SCHEMBL29907421 0.85 UGCG (0.78) UGCGSCN9AAXLMERTKMET
SCHEMBL29907342 0.85 UGCG (0.63) UGCGSCN9AAXLMERTKMET
SCHEMBL29907497 0.83 UGCG (0.81) UGCGSCN9AAXLMERTKMET
SCHEMBL29907394 0.81 UGCG (0.82) UGCGAXLMERTKMETGSK3A
SCHEMBL29907414 0.78 UGCG (0.71) UGCGSCN9AAXLMERTKMET
SCHEMBL29907392 0.77 UGCG (0.79) UGCGAXLMERTKMETTYRO3
SCHEMBL29907547 0.77 UGCG (0.64) UGCGSCN9AGSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220289679-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220289679-A1 HETEROCYCLIC COMPOUND GBA1, GBA2, GALC UGCG 10/4885SCN9A 1952/4885AXL 4241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.