Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364512 | 1.00 | S1PR4 (0.41) | S1PR4SLC40A1TLR7TRIM24TRIM33 | |
| SCHEMBL364488 | 0.88 | S1PR4 (0.41) | S1PR4SLC40A1TLR7TRIM24TRIM33 | |
| SCHEMBL364523 | 0.85 | S1PR4 (0.40) | S1PR4SLC40A1TLR7TRIM24TRIM33 | |
| SCHEMBL5582737 | 0.82 | S1PR4 (0.41) | S1PR4TLR7TRIM24TRIM33NPC1 | |
| SCHEMBL25352141 | 0.80 | S1PR4 (0.37) | S1PR4TRIM24TRIM33HDAC6NPC1 | |
| SCHEMBL5072839 | 0.80 | S1PR4 (0.45) | S1PR4TRIM24TRIM33NPC1HTT | |
| SCHEMBL13419577 | 0.78 | SLC40A1 (0.40) | SLC40A1SCN9ADYRK1ARXRARXRB | |
| SCHEMBL13419576 | 0.78 | SLC40A1 (0.43) | SLC40A1TLR7SCN9ACGASDYRK1A | |
| SCHEMBL5582739 | 0.77 | S1PR4 (0.46) | S1PR4TRIM24TRIM33SCN9AADORA2A | |
| SCHEMBL12368115 | 0.76 | SLC40A1 (0.43) | SLC40A1SCN9ADYRK1AADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-115181092-A | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-112279837-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-08-09 | — | — | CN | disclosed |