Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29907672 | 0.90 | ADORA2A (0.51) | ADORA2AADORA1ADORA2BBRD4DYRK1A | |
| SCHEMBL29907690 | 0.88 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BBRD4DYRK1A | |
| SCHEMBL21730185 | 0.83 | ADORA2A (0.66) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29907692 | 0.83 | ADORA2A (0.66) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22551920 | 0.77 | ADORA2A (0.67) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29907725 | 0.76 | ADORA2A (0.54) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29907696 | 0.75 | ADORA2A (0.46) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29907536 | 0.74 | ADORA2A (0.49) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21730376 | 0.73 | ADORA2A (0.48) | ADORA2AADORA1ADORA2BBRD4DYRK1A | |
| SCHEMBL18386991 | 0.71 | IRAK4 (0.48) | DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-A | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-112279837-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-08-09 | — | — | CN | disclosed |