Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 16/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29907725 | 0.89 | ADORA2A (0.54) | ADORA2AADORA1ADORA2BATR | |
| SCHEMBL29907536 | 0.87 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BATR | |
| SCHEMBL29907672 | 0.84 | ADORA2A (0.51) | ADORA2AADORA1ADORA2B | |
| SCHEMBL30175516 | 0.83 | ATR (0.46) | ADORA2AADORA1ADORA2BATRIRAK4 | |
| SCHEMBL29907690 | 0.77 | ADORA2A (0.49) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29907714 | 0.75 | ADORA2A (0.51) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29907604 | 0.74 | ADORA2A (0.61) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29907760 | 0.73 | IRAK4 (0.36) | ADORA2AADORA1ADORA2BIRAK4 | |
| SCHEMBL21722496 | 0.73 | ADORA2A (0.84) | ADORA2AADORA1ADORA2B | |
| SCHEMBL30175498 | 0.70 | ADORA2A (0.45) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-A | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-112279837-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-08-09 | — | — | CN | disclosed |