Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 15/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL871588 | 0.85 | IDO1 (0.63) | IDO1ADRA2AADRA2BPOLBSMN1; SMN2 | |
| SCHEMBL30538054 | 0.85 | IDO1 (0.63) | IDO1ADRA2AADRA2BPOLBSMN1; SMN2 | |
| SCHEMBL27820767 | 0.83 | IDO1 (0.51) | IDO1ADRA2APOLBSMN1; SMN2CYP3A4 | |
| SCHEMBL19044256 | 0.82 | IDO1 (0.51) | IDO1ADRA2AADRA2BPOLBSMN1; SMN2 | |
| SCHEMBL26259992 | 0.78 | ADRA2A (0.66) | IDO1ADRA2AADRA2BCYP3A4 | |
| SCHEMBL26260004 | 0.73 | IDO1 (0.58) | IDO1ADRA2AADRA2BCYP3A4 | |
| SCHEMBL31140103 | 0.73 | ADRA2A (0.63) | IDO1ADRA2AADRA2BPOLBSMN1; SMN2 | |
| SCHEMBL1948725 | 0.71 | IDO1 (1.00) | IDO1ADRA2AADRA2BCYP3A4 | |
| SCHEMBL13517203 | 0.71 | IDO1 (0.66) | IDO1ADRA2AADRA2BCYP3A4 | |
| SCHEMBL28226913 | 0.71 | AURKA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4554572-A2 | MIXTURES AND USES OF (2E)-3-(1,3-BENZODIOXOL-5-YL)-N-PHENYL-N-(TETRAHYDRO-3-FURANYL)-2-PROPENAMIDE | Symrise AG (DE) | 2025-05-21 | — | — | EP | disclosed |
| WO-2022207944-A9 | NOVEL MIXTURES AND USES OF (2E)-3-(1,3-BENZODIOXOL-5-YL)-N-PHENYL-N-(TETRAHYDRO-3-FURANYL)-2-PROPENAMIDE | SYMRISE AG (DE) | 2022-12-15 | — | — | WO | disclosed |
| WO-2022207944-A2 | NOVEL MIXTURES AND USES OF (2E)-3-(1,3-BENZODIOXOL-5-YL)-N-PHENYL-N-(TETRAHYDRO-3-FURANYL)-2-PROPENAMIDE | SYMRISE AG (DE) | 2022-10-06 | — | — | WO | disclosed |