SCHEMBL29907908

SCHEMBL29907908

CNC(=O)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 3/20 0.56
MDM4 O15151 3/20 0.56
TP53 P04637 3/20 0.56
KMT2A Q03164 1/20 0.51
TLR2 O60603 2/20 0.51
MDM2 Q00987 3/20 0.50
TNF P01375 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16343063 1.00 CASP3 (0.56) CASP3MDM4TP53KMT2ATLR2
SCHEMBL16218324 1.00 CASP3 (0.56) CASP3MDM4TP53KMT2ATLR2
SCHEMBL29907963 1.00 CASP3 (0.56) CASP3MDM4TP53KMT2ATLR2
SCHEMBL15083102 0.88 TLR2 (0.61) CASP3MDM4TP53KMT2ATLR2
SCHEMBL29540527 0.88 TLR2 (0.61) CASP3MDM4TP53KMT2ATLR2
SCHEMBL29540551 0.88 TLR2 (0.61) CASP3MDM4TP53KMT2ATLR2
SCHEMBL14445569 0.88 TLR2 (0.61) CASP3MDM4TP53KMT2ATLR2
SCHEMBL14559793 0.88 CASP3 (0.58) CASP3MDM4TP53KMT2ATLR2
SCHEMBL5385200 0.88 CASP3 (0.58) CASP3MDM4TP53KMT2ATLR2
SCHEMBL12138344 0.88 CASP3 (0.58) CASP3MDM4TP53KMT2ATLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PEPTIDREAM INC (JP) 2026-04-09 US disclosed
EP-4594336-A2 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PeptiDream Inc. (JP) 2025-08-06 EP disclosed
EP-4594337-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING EPHRIN TYPE-A RECEPTOR 2 AND USES THEREOF Rayzebio, Inc. (US) 2025-08-06 EP disclosed
US-20240167070-A1 METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Ny-HYDROXY- OR Ny-AMINO-L-ASPARAGINE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2024-05-23 US disclosed
WO-2024073622-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING EPHRIN TYPE-A RECEPTOR 2 AND USES THEREOF RAYZEBIO, INC. (US) 2024-04-04 WO disclosed
WO-2024073605-A2 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PEPTIDREAM INC. (JP) 2024-04-04 WO disclosed
WO-2022186782-A1 METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Nγ-HYDROXY- OR Nγ-AMINO-L-ASPARAGINE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-09-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240167070-A1 METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Ny-HYDROXY- OR Ny-AMINO-L-ASPARAGINE ANPEP, DNPEP, ASNS CASP3 4032/4885MDM4 4553/4885TP53 3680/4885
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME EPHA2, EPHA1, EPHB1 CASP3 4663/4885MDM4 1959/4885TP53 412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.