Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3044469 | 0.82 | MAPT (0.39) | HSD17B10KMT2AMEN1LMNAMAPT | |
| SCHEMBL16502242 | 0.82 | KMT2A (0.45) | KMT2ALMNAMAPTALDH1A1GAA | |
| SCHEMBL13828453 | 0.80 | SMN1; SMN2 (0.45) | KMT2ALMNAMAPTALDH1A1RAB9A | |
| SCHEMBL3707301 | 0.79 | GSK3B (0.46) | KMT2AMEN1SLC6A3MAPTALDH1A1 | |
| SCHEMBL3707298 | 0.79 | GSK3B (0.46) | KMT2AMEN1SLC6A3MAPTALDH1A1 | |
| SCHEMBL3710894 | 0.76 | SIRT1 (0.39) | KMT2AMEN1LMNASLC6A2SLC6A3 | |
| SCHEMBL3710891 | 0.76 | SIRT1 (0.39) | KMT2AMEN1LMNASLC6A2SLC6A3 | |
| SCHEMBL2292755 | 0.74 | CHRNA1 (0.54) | KMT2AMEN1SLC6A2SLC6A3MAPT | |
| SCHEMBL2292750 | 0.74 | CHRNA1 (0.54) | KMT2AMEN1SLC6A2SLC6A3MAPT | |
| SCHEMBL3701610 | 0.74 | NAPRT (0.43) | KMT2AMEN1MAPTGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174882-A1 | 5-MEMBERED HETEROCYCLYL CARBAMATE DERIVATIVES AS DUAL LPA RECEPTOR 1 AND LPA RECEPTOR 2 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2022-08-25 | — | — | WO | disclosed |