SCHEMBL29908043

SCHEMBL29908043

O=C(N[C@@H](Cc1ccc(F)cc1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.56
TP53 P04637 3/20 0.56
MDM2 Q00987 3/20 0.56
ALDH1A1 P00352 1/20 0.51
CASP3 P42574 2/20 0.49
PIN1 Q13526 1/20 0.49
GPR34 Q9UPC5 1/20 0.47
PTPN1 P18031 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2309871 1.00 MDM4 (0.56) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL29398165 1.00 MDM4 (0.56) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL119587 1.00 MDM4 (0.56) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL119362 1.00 MDM4 (0.56) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL29497566 1.00 MDM4 (0.56) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL32664665 0.97 MDM4 (0.54) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL30229662 0.97 MDM4 (0.54) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL3724680 0.97 MDM4 (0.54) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL3730210 0.97 MDM4 (0.54) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL3724684 0.97 MDM4 (0.54) MDM4TP53MDM2ALDH1A1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115053184-B Composition for forming EUV resist underlayer film 日产化学株式会社 2024-12-06 CN disclosed
CN-117279655-A Pharmaceutical use of cyclic peptide compounds 中外制药株式会社 2023-12-22 CN disclosed
CN-115053184-A Composition for forming EUV resist underlayer film 日产化学株式会社 2022-09-13 CN disclosed