SCHEMBL119362

SCHEMBL119362

O=C(N[C@@H](Cc1ccc(F)cc1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.56
TP53 P04637 3/20 0.56
MDM2 Q00987 3/20 0.56
ALDH1A1 P00352 1/20 0.51
CASP3 P42574 2/20 0.49
PIN1 Q13526 1/20 0.49
GPR34 Q9UPC5 1/20 0.47
PTPN1 P18031 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29908043 1.00 MDM4 (0.56) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL2309871 1.00 MDM4 (0.56) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL29398165 1.00 MDM4 (0.56) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL119587 1.00 MDM4 (0.56) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL29497566 1.00 MDM4 (0.56) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL32664665 0.97 MDM4 (0.54) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL30229662 0.97 MDM4 (0.54) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL3724680 0.97 MDM4 (0.54) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL3730210 0.97 MDM4 (0.54) MDM4TP53MDM2ALDH1A1CASP3
SCHEMBL3724684 0.97 MDM4 (0.54) MDM4TP53MDM2ALDH1A1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116922-A1 HIGHLY STABLE OXYTOCIN DERIVATIVES UNIVERSITAET WIEN (AT) 2026-04-30 US disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 US disclosed
US-20250376385-A1 PEROVSKITE POWDER, LIGHT EMITTING LAYER FOR LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING THE SAME SEOUL NAT UNIV R&DB FOUNDATION (KR) 2025-12-11 US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 US disclosed
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-29 US disclosed
EP-3303367-B1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2025-06-18 EP disclosed
US-20240400617-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-12-05 US disclosed
EP-4453003-A1 HIGHLY STABLE OXYTOCIN DERIVATIVES Universität Wien (AT) 2024-10-30 EP disclosed
US-20240215280-A1 IN SITU CORE/SHELL PEROVSKITE NANOCRYSTAL MATERIAL, METHOD OF PREPARATION THEREOF, AND LIGHT EMITTING DEVICE COMPRISING THE SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2024-06-27 US disclosed
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME UNIV NEW YORK (US) 2024-06-13 US disclosed
US-20040224985-A1 Melanocortin receptor ligands THE PROCTER & GAMBLE COMPANY 2004-11-11 US disclosed
WO-2004072076-A1 SUBSTITUTED HEXAHYDROPYRAZINO(1,2-A)PYRIMIDIN-4,7-DION DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-08-26 WO disclosed
EP-1390361-A2 MELANOCORTIN RECEPTOR LIGANDS THE PROCTER & GAMBLE COMPANY (US) 2004-02-25 EP disclosed
US-20040014676-A1 SRC kinase inhibitors useful for treating osteoporosis ARIAD PHARMACEUTICALS INC. 2004-01-22 US disclosed
US-20030109556-A1 Melanocortin receptor ligands THE PROCTER & GAMBLE COMPANY 2003-06-12 US disclosed
US-6548637-B1 Endomorphine analog analgesics SEPRACOR, INC. 2003-04-15 US disclosed
US-6482921-B1 Uridyl peptide antibiotic (UPA) derivatives, their synthesis and use ESSENTIAL THERAPEUTICS, INC. 2002-11-19 US disclosed
WO-2002085925-A2 MELANOCORTIN RECEPTOR LIGANDS THE PROCTER & GAMBLE COMPANY (US) 2002-10-31 WO disclosed
WO-2000044335-A2 URIDYL PEPTIDE ANTIBIOTIC (UPA) DERIVATIVES, THEIR SYNTHESIS AND USE MICROCIDE PHARMACEUTICALS, INC. (US) 2000-08-03 WO disclosed
WO-1999065932-A1 TETRAPEPTIDES, ANALOGS AND PEPTIDOMIMETICS WHICH BIND SELECTIVELY MAMMALIAN OPIOID RECEPTORS SEPRACOR, INC. (US) 1999-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109556-A1 Melanocortin receptor ligands MC3R, MC4R, MC1R MDM4 3065/4885TP53 4022/4885MDM2 3635/4885
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH MDM4 2743/4885TP53 3446/4885MDM2 777/4885
US-20240400617-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION KRAS, NRAS, HRAS MDM4 441/4885TP53 34/4885MDM2 164/4885
US-20040014676-A1 SRC kinase inhibitors useful for treating osteoporosis SRC, CTTN, YES1 MDM4 2715/4885TP53 1918/4885MDM2 1185/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 MDM4 2407/4885TP53 2772/4885MDM2 908/4885
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action KRAS, NRAS, HRAS MDM4 441/4885TP53 34/4885MDM2 164/4885
US-20040224985-A1 Melanocortin receptor ligands MC3R, MC4R, MC1R MDM4 3065/4885TP53 4022/4885MDM2 3635/4885
US-20260116922-A1 HIGHLY STABLE OXYTOCIN DERIVATIVES OXTR, CRH, TRHR MDM4 4514/4885TP53 4532/4885MDM2 3967/4885
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH MDM4 2503/4885TP53 3371/4885MDM2 678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.