Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 9/20 | 0.76 |
| ▸ | RAB9A | P51151 | 9/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.76 |
| ▸ | NPC1 | O15118 | 8/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | THRB | P10828 | 1/20 | 0.76 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | NSUN3 | Q9H649 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28573489 | 1.00 | STAT3 (1.00) | STAT3MEN1RAB9AKMT2ANPC1 | |
| SCHEMBL11149506 | 0.86 | KMT2A (1.00) | STAT3MEN1RAB9AKMT2ANPC1 | |
| SCHEMBL12974212 | 0.86 | NPC1 (0.78) | STAT3MEN1RAB9AKMT2ANPC1 | |
| SCHEMBL29908278 | 0.86 | NPC1 (0.78) | STAT3MEN1RAB9AKMT2ANPC1 | |
| SCHEMBL10253103 | 0.85 | NPC1 (0.76) | STAT3MEN1RAB9AKMT2ANPC1 | |
| SCHEMBL2681128 | 0.85 | STAT3 (1.00) | STAT3MEN1RAB9AKMT2ANPC1 | |
| SCHEMBL1804666 | 0.84 | NPC1 (0.76) | STAT3MEN1RAB9AKMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL28423065 | 0.84 | NPC1 (0.74) | STAT3MEN1RAB9AKMT2ANPC1 | |
| SCHEMBL28478834 | 0.84 | STAT3 (1.00) | STAT3MEN1RAB9AKMT2ANPC1 | |
| SCHEMBL29908282 | 0.84 | STAT3 (1.00) | STAT3MEN1RAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116456980-A | Application of thiazole compounds in preparation of medicines for treating and preventing cancers | 北京大学 | 2023-07-18 | — | — | CN | disclosed |
| WO-2022206084-A1 | USE OF THIAZOLE COMPOUND IN PREPARATION OF DRUG FOR TREATING AND PREVENTING CANCER | 北京大学 | 2022-10-06 | — | — | WO | disclosed |