SCHEMBL29908323

SCHEMBL29908323

NC(=O)n1cnc2cccnc21

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.56
TP53 P04637 2/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
PABPC1 P11940 1/20 0.46
POLB P06746 1/20 0.40
MAPT P10636 3/20 0.39
ELANE P08246 1/20 0.38
PDE4B Q07343 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30814447 0.84 KMT2A (0.50) PARP1TP53KMT2AMEN1PABPC1
SCHEMBL2715939 0.84 KMT2A (0.50) PARP1TP53KMT2AMEN1PABPC1
SCHEMBL112349 0.82 ELANE (0.48) PARP1TP53KMT2AMEN1PABPC1
SCHEMBL2180309 0.78 KMT2A (0.46) TP53KMT2AMEN1PABPC1MAPT
SCHEMBL27582571 0.78 TP53 (0.46) PARP1TP53KMT2AMEN1PABPC1
Carbamic Acid SCHEMBL10888970 0.75 SMN1; SMN2 (0.56) KMT2AMEN1MAPT
SCHEMBL10423399 0.75 MEN1 (0.56) TP53KMT2AMEN1PABPC1
SCHEMBL30814349 0.74 POLB (0.43) TP53KMT2AMEN1PABPC1POLB
SCHEMBL828619 0.74 KMT2A (0.57) KMT2AMEN1MAPT
SCHEMBL11882632 0.74 KMT2A (0.57) KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022188203-A1 IMIDAZOPYRIDINE DERIVATIVE 北京富龙康泰生物技术有限公司 2022-09-15 WO disclosed