Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | STAT6 | P42226 | 1/20 | 0.54 |
| ▸ | ASAH1 | Q13510 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11882632 | 1.00 | KMT2A (0.57) | KMT2ASMN1; SMN2LMNASTAT6ASAH1 | |
| Bromide SCHEMBL7400039 | 0.98 | KMT2A (0.55) | KMT2ASMN1; SMN2LMNASTAT6ASAH1 | |
| Hydrochloric Acid SCHEMBL738023 | 0.98 | KMT2A (0.55) | KMT2ASMN1; SMN2LMNASTAT6ASAH1 | |
| SCHEMBL7611308 | 0.98 | KMT2A (0.55) | KMT2ASMN1; SMN2LMNASTAT6ASAH1 | |
| Carbamic Acid SCHEMBL10888970 | 0.96 | SMN1; SMN2 (0.56) | KMT2ASMN1; SMN2LMNASTAT6ASAH1 | |
| SCHEMBL250172 | 0.84 | HTT (0.66) | KMT2ASMN1; SMN2LMNASTAT6ASAH1 | |
| SCHEMBL11443588 | 0.84 | KMT2A (0.60) | KMT2ASMN1; SMN2LMNASTAT6ASAH1 | |
| SCHEMBL857765 | 0.82 | SMN1; SMN2 (0.61) | KMT2ASMN1; SMN2LMNASTAT6ASAH1 | |
| SCHEMBL5133119 | 0.81 | KMT2A (0.57) | KMT2ASMN1; SMN2LMNASTAT6ASAH1 | |
| SCHEMBL5469156 | 0.81 | SMN1; SMN2 (0.54) | KMT2ASMN1; SMN2LMNASTAT6ASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 453 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024109642-A1 | USE OF BENZOAZACYCLIC COMPOUND AS ALLOSTERIC MODULATOR OF β2-ADRENOCEPTOR | 常州大学 | 2024-05-30 | — | — | WO | claimed |
| CN-117430737-A | Catalyst component for olefin polymerization, catalyst and application thereof | 中国石油化工股份有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-117430738-A | Catalyst component for olefin polymerization, catalyst and application thereof | 中国石油化工股份有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-108383795-B | 1-benzimidazole-N-amide derivative and preparation method thereof | 深圳市迪克曼科技开发有限公司 | 2021-05-11 | — | — | CN | claimed |
| US-20200237762-A1 | USE OF RNAI INHIBITING PARP ACTIVITY FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF CANCER | THE UNIVERSITY OF SHEFFIELD (GB) | 2020-07-30 | — | — | US | claimed |
| CN-110294754-A | Pyrido benzimidazole cysteine ratio probes and its application | 泰山医学院 | 2019-10-01 | — | — | CN | claimed |
| US-20180000822-A1 | Use of RNAI Inhibiting PARP Activity for the Manufacture of a Medicament for the Treatment of Cancer | THE UNIVERSITY OF SHEFFIELD (GB) | 2018-01-04 | — | — | US | claimed |
| CN-102935230-B | The RNAi of suppression PARP activity is for producing the purposes of the medicine for the treatment of cancer | 设菲尔德大学 | 2016-08-10 | — | — | CN | claimed |
| EP-1643991-B1 | BENZIMIDAZOLE CARBOXAMIDES AS RAF KINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2014-03-12 | — | — | EP | claimed |
| CN-101212903-B | Polycyclic carbamoylpyridone derivatives having HIV integrase inhibitory activity | SHIONOGI & CO | 2013-07-24 | — | — | CN | claimed |
| US-20050143504-A1 | Polytrimethylene terephthalate resins with improved properties | ZIMMER AG (DE) | 2005-06-30 | — | — | US | claimed |
| WO-2005004863-A1 | BENZIMIDAZOLE CARBOXAMIDES AS RAF KINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2005-01-20 | — | — | WO | claimed |
| EP-1490064-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | Pharmacia Corporation (US) | 2004-12-29 | — | — | EP | claimed |
| EP-1487899-A1 | POLYTRIMETHYLENE TEREPHTHALATE RESINS WITH IMPROVED PROPERTIES | Zimmer AG (DE) | 2004-12-22 | — | — | EP | claimed |
| WO-2003080702-A1 | POLYTRIMETHYLENE TEREPHTHALATE RESINS WITH IMPROVED PROPERTIES | ZIMMER AG (DE) | 2003-10-02 | — | — | WO | claimed |
| WO-2003068230-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORPORATION (US) | 2003-08-21 | — | — | WO | claimed |
| EP-1239882-A2 | FORMULATIONS OF ADENOSINE A1 AGONISTS | GLAXO GROUP LIMITED (GB) | 2002-09-18 | — | — | EP | claimed |
| WO-2001045685-A2 | FORMULATIONS OF ADENOSINE A1 AGONISTS | GLAXO GROUP LIMITED (GB) | 2001-06-28 | — | — | WO | claimed |
| WO-2001042224-A1 | CARBOXYAMIDO DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2001-06-14 | — | — | WO | claimed |
| US-5521193-A | SEROTONIN AGONISTS AND ANTAGONISTS | G. D. SEARLE & CO. (US) | 1996-05-28 | — | — | US | claimed |