Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577064 | 1.00 | CYP1A1 (0.39) | CYP1A1CYP1A2CYP1B1PDE5AABCG2 | |
| SCHEMBL23601201 | 0.92 | GRM5 (0.36) | PDE5AABCG2MAPTSMN1; SMN2CSNK2A1 | |
| SCHEMBL23601182 | 0.90 | PDE5A (0.33) | PDE5AABCG2MAPTSMN1; SMN2CSNK2A1 | |
| SCHEMBL23577272 | 0.88 | ABCG2 (0.32) | PDE5AABCG2MAPTSMN1; SMN2CSNK2A1 | |
| SCHEMBL29909592 | 0.88 | ABCG2 (0.32) | PDE5AABCG2MAPTSMN1; SMN2CSNK2A1 | |
| SCHEMBL23600546 | 0.88 | ALOX15 (0.33) | CYP1A2PDE5AABCG2MAPTSMN1; SMN2 | |
| SCHEMBL23601418 | 0.88 | PDE5A (0.34) | PDE5AABCG2MAPTSMN1; SMN2CSNK2A1 | |
| SCHEMBL23601193 | 0.88 | ABCG2 (0.44) | CYP1A2PDE5AABCG2MAPTSMN1; SMN2 | |
| SCHEMBL23576696 | 0.87 | CYP1A2 (0.33) | CYP1A2PDE5AABCG2MAPTSMN1; SMN2 | |
| SCHEMBL23577025 | 0.87 | SLC6A4 (0.34) | PDE5AABCG2MAPTSMN1; SMN2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-B1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES INC (JP) | 2024-09-18 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |