Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577040 | 1.00 | EGFR (0.43) | EGFRKDRPDGFRBRXRARXRB | |
| SCHEMBL29210686 | 1.00 | EGFR (0.43) | EGFRKDRPDGFRBRXRARXRB | |
| SCHEMBL30013725 | 1.00 | EGFR (0.43) | EGFRKDRPDGFRBRXRARXRB | |
| SCHEMBL29210603 | 0.93 | EGFR (0.41) | EGFRKDRPDGFRBRXRARXRB | |
| SCHEMBL23577087 | 0.93 | EGFR (0.41) | EGFRKDRPDGFRBRXRARXRB | |
| SCHEMBL30013226 | 0.93 | EGFR (0.41) | EGFRKDRPDGFRBRXRARXRB | |
| SCHEMBL29909240 | 0.93 | EGFR (0.41) | EGFRKDRPDGFRBRXRARXRB | |
| SCHEMBL23601321 | 0.88 | EGFR (0.42) | EGFRKDRPDGFRBRXRARXRB | |
| SCHEMBL29141395 | 0.88 | EGFR (0.42) | EGFRKDRPDGFRBRXRARXRB | |
| SCHEMBL30146701 | 0.88 | EGFR (0.42) | EGFRKDRPDGFRBRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |