Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577565 | 1.00 | HPGD (0.37) | HPGDKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL29909034 | 0.85 | MAPT (0.35) | KDM4EALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL23576890 | 0.85 | MAPT (0.35) | KDM4EALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL23601001 | 0.85 | FNTA (0.35) | HPGDKDM4EHSD17B10POLBMAPT | |
| SCHEMBL23577105 | 0.84 | PDE5A (0.34) | POLBMAPTFNTAFNTBTP53 | |
| SCHEMBL29909358 | 0.84 | PDE5A (0.34) | POLBMAPTFNTAFNTBTP53 | |
| SCHEMBL30920925 | 0.82 | TP53 (0.39) | POLBMAPTFNTAFNTBTP53 | |
| SCHEMBL23601235 | 0.82 | FNTA (0.40) | HPGDKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL29909768 | 0.82 | FNTA (0.40) | HPGDKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL23576641 | 0.80 | FNTA (0.35) | KDM4EALDH1A1POLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |