Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAT2A | P31153 | 2/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577105 | 1.00 | PDE5A (0.34) | PDE5AFNTAFNTBSOS1TP53 | |
| SCHEMBL23576890 | 0.90 | MAPT (0.35) | PDE5AFNTAFNTBSOS1TP53 | |
| SCHEMBL29909034 | 0.90 | MAPT (0.35) | PDE5AFNTAFNTBSOS1TP53 | |
| SCHEMBL23601001 | 0.86 | FNTA (0.35) | FNTAFNTBTP53MAPTMAT2A | |
| SCHEMBL23601648 | 0.85 | ALDH1A1 (0.38) | TP53MAPTPOLBEGFR | |
| SCHEMBL29909013 | 0.84 | HPGD (0.37) | FNTAFNTBTP53MAPTMAT2A | |
| SCHEMBL23577565 | 0.84 | HPGD (0.37) | FNTAFNTBTP53MAPTMAT2A | |
| SCHEMBL30920925 | 0.82 | TP53 (0.39) | PDE5AFNTAFNTBTP53MAPT | |
| SCHEMBL23601235 | 0.82 | FNTA (0.40) | FNTAFNTBTP53MAPTMAT2A | |
| SCHEMBL29909768 | 0.82 | FNTA (0.40) | FNTAFNTBTP53MAPTMAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |