Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576621 | 1.00 | ABCG2 (0.45) | ABCG2DHODHSMN1; SMN2PDE5AMAPT | |
| SCHEMBL23601567 | 0.93 | ABCG2 (0.51) | ABCG2DHODHSMN1; SMN2PDE5AALDH1A1 | |
| SCHEMBL29909289 | 0.93 | ABCG2 (0.51) | ABCG2DHODHSMN1; SMN2PDE5AALDH1A1 | |
| SCHEMBL23578033 | 0.92 | PDE5A (0.44) | ABCG2DHODHSMN1; SMN2PDE5AALDH1A1 | |
| SCHEMBL29909882 | 0.90 | ALDH1A1 (0.39) | ABCG2DHODHSMN1; SMN2PDE5AMAPT | |
| SCHEMBL23578009 | 0.90 | ALDH1A1 (0.39) | ABCG2DHODHSMN1; SMN2PDE5AMAPT | |
| SCHEMBL29909772 | 0.89 | FNTA (0.40) | ABCG2SMN1; SMN2PDE5AMAPTALDH1A1 | |
| SCHEMBL23577687 | 0.89 | ABCG2 (0.38) | ABCG2DHODHSMN1; SMN2PDE5AMAPT | |
| SCHEMBL23576825 | 0.89 | FNTA (0.40) | ABCG2SMN1; SMN2PDE5AMAPTALDH1A1 | |
| SCHEMBL23577126 | 0.89 | TACR1 (0.40) | ABCG2DHODHSMN1; SMN2PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |