Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576628 | 1.00 | ABCG2 (0.38) | ABCG2PDE5APDGFRBEGFRKDR | |
| SCHEMBL23576865 | 0.93 | MAPT (0.33) | ABCG2PDE5APDGFRBEGFRKDR | |
| SCHEMBL29909031 | 0.93 | MAPT (0.33) | ABCG2PDE5APDGFRBEGFRKDR | |
| SCHEMBL29909127 | 0.92 | FNTA (0.36) | ABCG2PDE5APDGFRBEGFRKDR | |
| SCHEMBL23577060 | 0.92 | FNTA (0.36) | ABCG2PDE5APDGFRBEGFRKDR | |
| SCHEMBL23577341 | 0.91 | PDE5A (0.36) | PDE5APDGFRBEGFRKDRMAPT | |
| SCHEMBL29909238 | 0.91 | PDE5A (0.36) | PDE5APDGFRBEGFRKDRMAPT | |
| SCHEMBL23576713 | 0.90 | OPRD1 (0.34) | ABCG2PDGFRBMAPTGABRA1GABRG2 | |
| SCHEMBL23576643 | 0.90 | NPM1 (0.39) | PDGFRBEGFRKDRMAPTGABRG2 | |
| SCHEMBL29909114 | 0.90 | NPM1 (0.39) | PDGFRBEGFRKDRMAPTGABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |