Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.31 |
| ▸ | ICMT | O60725 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577367 | 1.00 | ABCG2 (0.33) | ABCG2DHODHTP53SMN1; SMN2OPRD1 | |
| SCHEMBL23577238 | 0.90 | ABCG2 (0.35) | ABCG2DHODHTP53SMN1; SMN2OPRD1 | |
| SCHEMBL29909506 | 0.90 | ABCG2 (0.35) | ABCG2DHODHTP53SMN1; SMN2OPRD1 | |
| SCHEMBL29909794 | 0.87 | FNTA (0.34) | ABCG2DHODHOPRD1ICMTFNTA | |
| SCHEMBL23577282 | 0.87 | ABCG2 (0.33) | ABCG2DHODHOPRD1FNTAFNTB | |
| SCHEMBL29909455 | 0.87 | ABCG2 (0.33) | ABCG2DHODHOPRD1FNTAFNTB | |
| SCHEMBL23577166 | 0.87 | FNTA (0.34) | ABCG2DHODHOPRD1ICMTFNTA | |
| SCHEMBL23576866 | 0.85 | MGLL (0.35) | TP53SMN1; SMN2OPRD1FNTAFNTB | |
| SCHEMBL29909218 | 0.85 | MGLL (0.35) | TP53SMN1; SMN2OPRD1FNTAFNTB | |
| SCHEMBL23577223 | 0.85 | DHODH (0.33) | ABCG2DHODHFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |