Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576737 | 1.00 | ABCG2 (0.52) | ABCG2ALDH1A1L3MBTL1GSK3BCYP19A1 | |
| SCHEMBL23578021 | 0.94 | ABCG2 (0.45) | ABCG2ALDH1A1DHODHHRH4HRH3 | |
| SCHEMBL29909003 | 0.94 | ABCG2 (0.45) | ABCG2ALDH1A1DHODHHRH4HRH3 | |
| SCHEMBL29909490 | 0.93 | ABCG2 (0.44) | ABCG2ALDH1A1DHODHHRH4HRH3 | |
| SCHEMBL23576891 | 0.93 | ABCG2 (0.44) | ABCG2ALDH1A1DHODHHRH4HRH3 | |
| SCHEMBL23577151 | 0.92 | ABCG2 (0.47) | ABCG2ALDH1A1L3MBTL1GSK3BCYP19A1 | |
| SCHEMBL30014094 | 0.92 | ABCG2 (0.47) | ABCG2ALDH1A1L3MBTL1GSK3BCYP19A1 | |
| SCHEMBL23577259 | 0.91 | ABCG2 (0.43) | ABCG2ALDH1A1NPBWR1NPSR1MAPT | |
| SCHEMBL29909220 | 0.91 | ABCG2 (0.43) | ABCG2ALDH1A1NPBWR1NPSR1MAPT | |
| SCHEMBL23601765 | 0.88 | ABCG2 (0.44) | ABCG2ALDH1A1HRH4HRH3NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |