Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576891 | 1.00 | ABCG2 (0.44) | ABCG2DHODHTAAR1HRH4HRH3 | |
| SCHEMBL29909184 | 0.93 | ABCG2 (0.52) | ABCG2DHODHHRH4HRH3KEAP1 | |
| SCHEMBL23576737 | 0.93 | ABCG2 (0.52) | ABCG2DHODHHRH4HRH3KEAP1 | |
| SCHEMBL29909003 | 0.92 | ABCG2 (0.45) | ABCG2DHODHHRH4HRH3KEAP1 | |
| SCHEMBL23578021 | 0.92 | ABCG2 (0.45) | ABCG2DHODHHRH4HRH3KEAP1 | |
| SCHEMBL24721496 | 0.90 | ABCG2 (0.43) | ABCG2HRH4HRH3KEAP1NFE2L2 | |
| SCHEMBL29909220 | 0.90 | ABCG2 (0.43) | ABCG2ALDH1A1SMN1; SMN2 | |
| SCHEMBL23577259 | 0.90 | ABCG2 (0.43) | ABCG2ALDH1A1SMN1; SMN2 | |
| SCHEMBL24721427 | 0.87 | ABCG2 (0.41) | ABCG2ALDH1A1SMN1; SMN2 | |
| SCHEMBL29909355 | 0.87 | ABCG2 (0.41) | ABCG2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |