Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | HK1 | P19367 | 2/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576640 | 1.00 | PTAFR (0.33) | PTAFRNQO2MAPTKDM4EMAPK1 | |
| SCHEMBL23601062 | 0.90 | HTT (0.38) | PTAFRNQO2MAPTKDM4EMAPK1 | |
| SCHEMBL29909393 | 0.80 | PTAFR (0.35) | PTAFR | |
| SCHEMBL24721236 | 0.80 | PTAFR (0.35) | PTAFR | |
| SCHEMBL23601058 | 0.79 | MAPT (0.34) | PTAFRNQO2MAPTPTGDR2SMN1; SMN2 | |
| SCHEMBL23601890 | 0.74 | TP53 (0.39) | MAPTKDM4EMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30013647 | 0.72 | ABCG2 (0.35) | MAPTKDM4EALDH1A1 | |
| SCHEMBL23577618 | 0.72 | ABCG2 (0.35) | MAPTKDM4EALDH1A1 | |
| SCHEMBL23601469 | 0.72 | NQO2 (0.32) | PTAFRNQO2 | |
| SCHEMBL23577346 | 0.71 | PTAFR (0.33) | PTAFRNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |