Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24721236 | 1.00 | PTAFR (0.35) | PTAFRMAP3K14GRM5 | |
| SCHEMBL23576642 | 0.86 | SMN1; SMN2 (0.31) | MAP3K14 | |
| SCHEMBL29909520 | 0.86 | SMN1; SMN2 (0.31) | MAP3K14 | |
| SCHEMBL23601062 | 0.82 | HTT (0.38) | PTAFR | |
| SCHEMBL29909164 | 0.82 | PTAFR (0.32) | PTAFR | |
| SCHEMBL23577576 | 0.82 | PTAFR (0.32) | PTAFR | |
| SCHEMBL29909326 | 0.81 | PTAFR (0.33) | PTAFR | |
| SCHEMBL24721441 | 0.81 | PTAFR (0.33) | PTAFR | |
| SCHEMBL23576640 | 0.80 | PTAFR (0.33) | PTAFR | |
| SCHEMBL29909197 | 0.80 | PTAFR (0.33) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |